4-BROMOPHENYLACETIC ACID CHLORIDE

4-BROMOPHENYLACETIC ACID CHLORIDE - Names and Identifiers

Name	4-Bromophenylacetyl chloride
Synonyms	SKL1305 4-Bromophenylacetyl chloride (4-Bromophenyl)acetyl chloride Benzeneacetyl chloride,4-bromo- (4-BROMO-PHENYL)-ACETYL CHLORIDE 4-BROMOPHENYLACETIC ACID CHLORIDE 4-Bromophenylacetic acid chloride 2-(4-bromophenyl)ethanoyl chloride 2-(4-bromophenyl)acetic acid chloride
CAS	37859-24-8
InChI	InChI=1/C8H6BrClO/c9-7-3-1-6(2-4-7)5-8(10)11/h1-4H,5H2

4-BROMOPHENYLACETIC ACID CHLORIDE - Physico-chemical Properties

Molecular Formula	C8H6BrClO
Molar Mass	233.49
Density	1.573 g/mL at 25 °C
Boling Point	180-185°C/10mm
Flash Point	>110℃
Vapor Presure	0.00296mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.572

4-BROMOPHENYLACETIC ACID CHLORIDE - Risk and Safety

Hazard Symbols	C - Corrosive
Risk Codes	R34 - Causes burns R22 - Harmful if swallowed
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
UN IDs	3265
WGK Germany	3

4-BROMOPHENYLACETIC ACID CHLORIDE - Introduction

4-Bromophenylacetyl chloride is an organic compound with the chemical formula C8H6BrClO. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 4-Bromophenylacetyl chloride is a colorless to pale yellow liquid.
-Odor: It has a pungent odor.
-Solubility: Soluble in organic solvents such as ethanol, chloroform and dichloromethane.
-Melting point: about 30-32°C.
-Boiling point: about 220°C.

Use:
4-Bromophenylacetyl chloride can be used as an important intermediate in organic synthesis and is often used in the synthesis of other organic compounds, such as drugs, dyes and pesticides. It can participate in benzene ring substitution reaction, acid anhydride reaction and acylation reaction.

Preparation Method:
A common preparation method is to react 4-bromoacetophenone with thionyl chloride. 4-Bromoacetophenone is first reacted with thionyl chloride under appropriate reaction conditions to give 4-Bromophenylacetyl chloride as the product.

Safety Information:
- 4-Bromophenylacetyl chloride is an irritant compound that may cause eye, skin and respiratory tract irritation on direct contact. Wear appropriate protective gloves, glasses and masks for safe operation.
-It should be stored in a closed container, away from fire and heat sources.
-When using or handling, ensure that good ventilation conditions are provided to maintain air quality.

Please note that this compound is dangerous and should be used in a laboratory environment and follow correct safe operating procedures and operating instructions.

Last Update：2024-04-09 15:17:57